ABSTRACT
With the advent of COVID-19 as a pandemic, researchers and medical communities have taken up the quest to answer many questions. The science of the 21st century is seen to rely more on genetically modified animal models and cell lines for understanding the virus-host interactions and pathogenesis. This has put a shadow on basic yet effective conventional ways of conducting autopsy studies, collecting tissue samples, and examining them under a microscope. In this very moment of crisis, researchers are advised to study the disease in its natural micro-environment. Though newer advances in science and technology can help us in constructing the road ahead but that road can tread us to blind ends, without the guiding vision provided by a pathological autopsy © 2021, Journal of Indian Academy of Forensic Medicine.All Rights Reserved.
ABSTRACT
The coronavirus disease 2019 (COVID-2019) that emerged in Wuhan, China, has rapidly spread to many countries across all six WHO regions. However, its pathobiology remains incompletely understood and many efforts are underway to study it worldwide. To clarify its pathogenesis to some extent, it will inevitably require lots of COVID-2019-associated pathological autopsies. Pathologists from all over the world have raised concerns with pathological autopsy relating to COVID-2019. The issue of whether a person died from COVID-2019 infection or not is always an ambiguous problem in some cases, and ongoing epidemiology from China may shed light on it. This review retrospectively summarizes the research status of pathological autopsy for COVID-2019 deaths in China, which will be important for the cause of death, prevention, control and clinical strategies of COVID-2019. Moreover, it points out several challenges at autopsy. We believe pathological studies from China enable to correlate clinical symptoms and pathological features of COVID-2019 for doctors and provide an insight into COVID-2019 disease.